How to Lower Cortisol

Restore Hyper Wellness Writer
Restore Hyper Wellness Writer
6 minutes
April 1, 2025
Woman smiles, knowing how to lower cortisol with science-backed therapies at Restore Hyper Wellness

Should you really try to lower your cortisol? Our experts share what you should know.

Cortisol is often referred to as the "stress hormone." It plays a pivotal role in various bodily functions, including metabolism regulation, immune response and stress management.1 

While essential for survival, persistently elevated cortisol levels can lead to adverse health effects such as weight gain, hypertension and impaired cognitive function.2 This is why understanding cortisol and exploring ways to manage high cortisol is so important. 

What is Cortisol?

Cortisol is a glucocorticoid hormone produced by the adrenal glands in response to stress and low blood-glucose concentration. It helps increase blood sugar through gluconeogenesis and breaks down fat and protein.

We asked Dr. Rachele, our Director of Scientific Research & Education, and she stated, “Cortisol also plays an essential role in immune regulation, cardiovascular function, and stress adaptation by helping to regulate inflammation, supporting blood pressure, and enhancing cognitive function. While cortisol responds to environmental stimuli and is vital for overall homeostasis, its benefits rely on maintaining balanced levels to prevent negative effects from chronic elevation.”

What is the Cortisol Circadian Rhythm?

Did you know that cortisol has a circadian rhythm?

A circadian rhythm is a natural, internal process that regulates the sleep-wake cycle and repeats roughly every 24 hours. In humans, cortisol levels typically peak in the early morning hours, aiding in wakefulness and energy mobilization, and they gradually decline throughout the day, reaching the lowest point during the night.2 This rhythmic pattern is essential for various physiological processes, including metabolism, immune function and blood pressure regulation.

So, while you may see headlines that tout “lowering cortisol,” a flattened curve, where cortisol levels remain constant without peaks, can be detrimental. These disruptions to the natural cortisol circadian rhythm have been linked to conditions like chronic fatigue syndrome, insomnia and burnout.3 Maintaining a natural rise and fall in cortisol levels is crucial for synchronizing the body's internal clock with environmental cues, thereby promoting optimal health.4

Cortisol Can Become Chronically Elevated

“Although there are circadian peaks and recoveries to cortisol release, cortisol levels can become elevated due to chronic stress, disrupted circadian rhythms, medical conditions or lifestyle factors,” Dr. Rachele shared.

“The hypothalamic-pituitary-adrenal (HPA) axis regulates cortisol secretion, responding to stressors such as psychological distress, poor sleep, excessive exercise or illness. Chronic activation of the HPA axis—often driven by persistent stress or inflammation—leads to prolonged cortisol elevation, which can contribute to metabolic dysfunction, immune suppression and cardiovascular issues.5 Sleep deprivation and shift work also dysregulate cortisol rhythms, causing abnormal secretion patterns that may increase disease risk.6 Additionally, conditions such as Cushing’s syndrome result in excessive cortisol due to adrenal or pituitary dysfunction.7 Understanding the triggers of cortisol dysregulation is crucial for mitigating its long-term health effects.”

Learn more about Dr. Rachele Pojednic.

How to Lower Cortisol at Restore

Magnesium in IV Therapy

Magnesium plays a vital role in numerous biochemical reactions in the body, including those that regulate stress responses. Intravenous (IV) magnesium therapy has been shown to have a calming effect on the nervous system, potentially reducing cortisol levels and promoting relaxation.8 This method ensures rapid delivery and absorption of magnesium, making it a viable option for individuals with magnesium deficiencies or those seeking immediate relief from stress-induced symptoms.

Melt Stress With Heat

Studies have indicated that regular use of Infrared Saunas can help reduce stress and fatigue, potentially through the modulation of the nervous system and hormones, including cortisol levels.9 The heat exposure may also stimulate endorphin release, contributing to an overall sense of well-being.10

Chill Out With Cryotherapy

Cryotherapy utilizes the concept of hormesis, which suggests that moderate stressors, like cold exposure, can activate adaptive responses that improve health.11 Cryotherapy may stimulate the release of endorphins and reduce inflammation, contributing to stress reduction and enhanced mood.12

Take Some Deep Breaths With mHbOT

Mild Hyperbaric Oxygen Therapy (mHbOT) involves breathing enhanced oxygen in a pressurized environment. Combined, this increases oxygen availability to tissues. Enhanced oxygenation can improve cellular metabolism and promote healing.13 Some studies suggest that mHbOT may help reduce oxidative stress and inflammation, potentially leading to lower cortisol levels and improved stress management.14

Schedule Your Reset 

Incorporating these science-backed therapies can help manage cortisol levels and mitigate the adverse effects of chronic stress. Book your appointments today!

Medical services are provided by an independently-owned physician practice. Some services may require medical clearance and a prescription. We reserve the right to refuse service to anyone. Services, therapies, ingredients and prices may vary per location. The content on our site, blog posts, educational materials, app, promotional newsletters, and any other written content are not intended to replace an evaluation with a qualified healthcare professional and are not intended as medical advice.

  1. (2025, February 17). Cortisol. Cleveland Clinic. https://my.clevelandclinic.org/health/articles/22187-cortisol
  2. Azmani, S. (2021, January 14). Cortisol on Circadian Rhythm and Its Effect on Cardiovascular System. International Journal of Environmental Research and Public Health. https://www.mdpi.com/1660-4601/18/2/676
  3. Liu, P. (2021, June.) Sleep and circadian regulation of cortisol: A short review. Current Opinion in Endocrine and Metabolic Research. https://www.sciencedirect.com/science/article/pii/S2451965021000363?via%3Dihub
  4. Andreadi, A. (2025, February 27). Modified Cortisol Circadian Rhythm: The Hidden Toll of Night-Shift Work. International Journal of Molecular Sciences. https://www.mdpi.com/1422-0067/26/5/2090
  5. Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000). How do glucocorticoids influence stress responses? Endocrine Reviews, 21(1), 55-89. DOI: 10.1210/edrv.21.1.0389 
  6. Chrousos, G. P. (2009). Stress and disorders of the stress system. Nature Reviews Endocrinology, 5(7), 374-381. DOI: 10.1038/nrendo.2009.106
  7. Herman, J. P., McKlveen, J. M., Ghosal, S., et al. (2016). Regulation of the hypothalamic-pituitary-adrenocortical stress response. Comprehensive Physiology, 6(2), 603-621. DOI: 10.1002/cphy.c150015
  8. Pickering, G. (2020, November 28). Magnesium Status and Stress: The Vicious Circle Concept Revisited. Nutrients. https://pmc.ncbi.nlm.nih.gov/articles/PMC7761127/
  9. Henderson, K. (2021, January 27). The Cardiometabolic Health Benefits of Sauna Exposure in Individuals with High-Stress Occupations. A Mechanistic Review. International Journal of Environmental Research and Public Health. https://www.mdpi.com/1660-4601/18/3/1105
  10. Chang, M. (2023, November 27). A study on neural changes induced by sauna bathing: Neural basis of the “totonou” state. PLoSOne. https://pmc.ncbi.nlm.nih.gov/articles/PMC10681252/
  11. Panchenko, L. (2013). The evaluation of stressful influence of cryotherapy on the human body. European Psychiatry. https://www.sciencedirect.com/science/article/abs/pii/S0924933813772390
  12.  Rymaszewska, J. (2020, June 8). Efficacy of the Whole-Body Cryotherapy as Add-on Therapy to Pharmacological Treatment of Depression—A Randomized Controlled Trial. Frontiers. https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2020.00522/full
  13.  Castilla, D. (2012, November 29). Oxygen: Implications for Wound Healing. Advances in Wound Care. https://www.liebertpub.com/doi/10.1089/wound.2011.0319
  14.  Oyaizu, T. (2018, January 22). Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation. Nature.  https://www.nature.com/articles/s41598-018-19670-x